| 发明名称 |
THIAZOLES FOR THE TREATMENT OF PROLIFERATIVE DISORDERS |
| 摘要 |
<p>The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein R<SUB>a</SUB>, R<SUB>b</SUB>, and R<SUB>2</SUB> are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.</p> |
| 申请公布号 |
WO2007061909(A1) |
申请公布日期 |
2007.05.31 |
| 申请号 |
WO2006US44799 |
申请日期 |
2006.11.17 |
| 申请人 |
SYNTA PHARMACEUTICALS CORP.;SUN, LIJUN;JIANG, JUN;BORELLA, CHRISTOPHER;CHEN, SHOUJUN;KOYA, KEIZO |
发明人 |
SUN, LIJUN;JIANG, JUN;BORELLA, CHRISTOPHER;CHEN, SHOUJUN;KOYA, KEIZO |
| 分类号 |
C07D275/02;A61K31/425;A61P35/00 |
主分类号 |
C07D275/02 |
| 代理机构 |
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