| 摘要 |
THE PRESENT INVENTION PROVIDES A PROCESS FOR PREPARING ARIPIPRAZOLE IN A HIGH PURITY AND A HIGH YIELD. ACCORDING TO THE PROCESS OF THE PRESENT INVENTION, ARIPIPRAZOLE IS PREPARED BY THE REACTION OF A CARBOSTYRIL COMPOUND REPRESENTED BY GENERAL FORMULA (2): WHEREIN X IS HALOGEN ATOM, LOWER ALKANESULFONYLOXY GROUP, ARYLSULFONYLOXY GROUP OR AN ARALKYLSULFONYLOXY GROUP), WITH A PIPERAZINE COMPOUND REPRESENTED BY FORMULA (3) : AND/ OR A SALT THEREOF IN WATER, IN THE PRESENCE OF 0.5 TO 10 MOL OF AN INORGANIC BASIC COMPOUND, PER MOL OF THE CARBOSTYRIL COMPOUND (2)
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