A novel FSH mutant with increased glycosylation and longer half-lifes for use in inducing folliculogenesis in human patients is described. The FSH mutant permits the use of lower cumulative doses of FSH to achieve the same or better clinical result.
申请公布号
ZA200601803(B)
申请公布日期
2007.05.30
申请号
ZA20060001803
申请日期
2004.09.02
申请人
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
发明人
GARONE, LOUISE M;ARKINSTALL, STEPHEN J;BRONDYK, WILLIAM H;CAMPBELL, ROBERT K;JIANG, XULIANG;MCKENNA, SEAN D;TEPPER, MARK