发明名称 |
CD20-Binding polypeptide compositions |
摘要 |
A CD20-binding polypeptide composition comprising a combination of a modified heavy chain variable region polypeptide and a modified light chain variable region polypeptide. The combination can be (a) a modified 2B8 antibody heavy chain variable region polypeptide of SEQ ID NO: 48; and a modified 2B8 antibody light chain variable region polypeptide of SEQ ID NO: 49; or (b) a modified Leu16 antibody heavy chain variable region polypeptide of SEQ ID NO: 50; and a modified Leu16 antibody light chain variable region polypeptide of SEQ ID NO: 51. |
申请公布号 |
ZA200602110(B) |
申请公布日期 |
2007.05.30 |
申请号 |
ZA20060002110 |
申请日期 |
2006.03.13 |
申请人 |
MERCK PATENT GMBH |
发明人 |
CARR, FRANCIS J.;GILLIES, STEPHEN D.;WILLIAMS, STEPHEN |
分类号 |
A61K;A61P;A61P37/00;C07K;C07K16/28;C07K16/30;C12N;C12N15/13 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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