发明名称 |
Vectors for enhanced expression of VEGF for atrial disease treatment |
摘要 |
The invention provides a vector which is capable of the expression of a vascular endothelial growth factor wherein the vector comprises a modified PCMV promoter. The invention further provides use of a vector which is capable of and expressing a vascular endothelial growth factor (VEGF) for the regulation of endothelial function, angiogenesis and arteriogenesis. The invention further comprises use of a vector which is capable of the expression of a vascular endothelial growth factor (VEGF) for the prophylactic treatment of arterial diseases and/or bone marrow diseases and/or neural diseases.
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申请公布号 |
US7223740(B2) |
申请公布日期 |
2007.05.29 |
申请号 |
US20040478449 |
申请日期 |
2004.04.29 |
申请人 |
FORNIX BIOSCIENCES N.V. |
发明人 |
VISSER TJERK JOHANNES A.;ROOSSIEN FOLKERT FEIKO;UBINK-BONTEKOE CAROLA JACOBA M. |
分类号 |
A61K48/00;A61K38/18;C12N5/08;C12N15/00;C12N15/869 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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