发明名称 |
Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same |
摘要 |
The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan synthases from Pasteurella, in order to create a variety of glycosaminoglycan oligosaccharides having a natural or chimeric or hybrid sugar structure with a targeted size that are substantially monodisperse in size.
|
申请公布号 |
US7223571(B2) |
申请公布日期 |
2007.05.29 |
申请号 |
US20030642248 |
申请日期 |
2003.08.15 |
申请人 |
THE BOARD OF REGENTS OF THE UNIVERSTIY OF OKLAHOMA |
发明人 |
DEANGELIS PAUL L.;JING WEI |
分类号 |
C12P19/18;A61K9/00;A61K39/102;A61K47/36;A61L24/08;A61L27/20;A61L29/08;C07H3/06;C07K14/705;C07K16/28;C08B37/00;C12N9/10;C12P19/04;C12P19/26;C12Q1/68 |
主分类号 |
C12P19/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|