发明名称 3,3-Diphenylpropylamines, their use and preparation
摘要 The invention relates to 3,3-diphenylpropylamines of formula (I), wherein R<SUP>1 </SUP>signifies hydrogen or methyl, R<SUP>2 </SUP>and R<SUP>3 </SUP>independently signify hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphamoyl or halogen, and X represents a tertiary amino group of formula (II), wherein R<SUP>4 </SUP>and R<SUP>5 </SUP>signify non-aromatic hydrocarbyl groups, which may be the same or different and which together contain at least three carbon atoms, and wherein R<SUP>4 </SUP>and R<SUP>5 </SUP>may form a ring together with the amine nitrogen, their salts with physiologically acceptable acids and, when the compounds can be in the form of optical isomers, the racemic mixture and the individual enantiomers. The invention also relates to methods for their preparation, pharmaceutical compositions containing the novel compounds, and the use of the compounds for preparing drugs
申请公布号 USRE39667(E1) 申请公布日期 2007.05.29
申请号 US19930017635D 申请日期 1993.11.05
申请人 PFIZER HEALTH AB 发明人 JOHANSSON ROLF A.;MOSES PINCHAS;NILVEBRANT LISBETH;SPARF BENGT A.
分类号 C07C215/76;C07D295/08;A61K31/135;A61K31/195;A61K31/235;A61K31/40;A61K31/445;A61P25/02;C07B57/00;C07C215/54;C07C217/62;C07D207/06;C07D211/14;C07D211/16 主分类号 C07C215/76
代理机构 代理人
主权项
地址