| 发明名称 |
NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS |
| 摘要 |
The present invention relates to novel compounds of formula I wherein W, n, X and W' are defined in the description; invention compounds are modulators of metabotropic glutamate receptors - subtype 5 ("mGluR5") which are useful for the treatment of central nervous system disorders as well as other disorders modulated by mGluR5 receptors. |
| 申请公布号 |
KR20070054624(A) |
申请公布日期 |
2007.05.29 |
| 申请号 |
KR20077000847 |
申请日期 |
2005.06.17 |
| 申请人 |
ADDEX PHARMACEUTICALS SA |
发明人 |
BESSIS ANNE SOPHIE;BOLEA CHRISTELLE;BONNET BEATRICE;EPPING JORDAN MARK;POIRIER NICHOLAS;POLI SONIA MARIA;ROCHER JEAN PHILIPPE;THOLLON YVES |
| 分类号 |
C07D401/06;A61K31/4035;A61K31/4196;A61K31/422;A61K31/423;A61K31/4245;A61K31/427;A61K31/428;A61K31/44;A61K31/4427;A61K31/47;A61K31/4709;A61K31/506;A61P25/28;C07D213/56;C07D215/06;C07D233/54;C07D239/26;C07D263/56;C07D277/22;C07D403/06;C07D413/06;C07D417/06;C07D471/04;C07D498/04 |
主分类号 |
C07D401/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
