| 摘要 |
FIELD: medical-destination materials and products. ^ SUBSTANCE: preparation of hydroxyapatite-based porous ceramic granules, which can be used to fill bone defects in traumatology, orthopedics, maxillofacial surgery, and surgical stomatology, comprises preliminary synthesis of calcium phosphate powder with Ca/P ratio 1.5-1.67 and preparing suspension with 10% gelatin solution in proportion of 0.5-3 mL solution per 1 g powder at solution temperature 10 to 39° C. Suspension of hydroxyapatite in aqueous gelatin solution is then dispersed in neutral liquid vegetable oil, resulting mixture is stirred by blade stirrer at rotation speed 100 to 1500 rpm. Under effect of surface tension, spherical granules are formed, which are washed, dried, and subjected to heat treatment at 900-1250° C. ^ EFFECT: enabled preparation of granules with controlled size and open porosity occupying 20 to 80% of the volume. ^ 1 tbl, 4 ex |
