| 发明名称 |
INDOLE-2-CARBOXAMIDES AS INHIBITORS OF FACTOR Xa AND/OR VIIa, MEDICINAL AGENT BASED ON THEREOF AND METHOD FOR THEIR PREPARING |
| 摘要 |
<p>FIELD: organic chemistry, medicine, hematology, pharmacy. ^ SUBSTANCE: invention relates to novel compounds of the formula (I): in all their stereoisomeric forms and their mixtures taken in any ratio and their physiologically acceptable salts possessing properties of inhibitors of factor Xa and/or factor VIIa, and to a medicinal agent based on thereof. Also, invention relates to a method for synthesis of these compounds and their using for preparing pharmaceutical agents for inhibition of activity of factor Xa and/or factor VIIa or for their effect on blood coagulation or fibrinolysis. ^ EFFECT: valuable medicinal properties of compounds and pharmaceutical composition. ^ 10 cl, 1 tbl, 276 ex</p> |
| 申请公布号 |
RU2299881(C2) |
申请公布日期 |
2007.05.27 |
| 申请号 |
RU20040118710 |
申请日期 |
2002.11.08 |
| 申请人 |
SANOFI-AVENTIS DOJCHLAND GMBKH |
发明人 |
NAZARE MARK;EHSSRIKH MELANI;UILL DEHVID UILL'JAM;MATTER KHANS;RITTER KURT;VENER FOL'KMAR |
| 分类号 |
C07D209/42;A61K31/404;A61K31/405;A61K31/422;A61K31/4439;A61K31/454;A61K31/4545;A61K31/4725;A61K31/496;A61K31/506;A61K31/517;A61P7/02;A61P9/00;A61P9/08;A61P9/10;A61P29/00;A61P43/00;C07D209/22;C07D401/06;C07D401/12;C07D401/14;C07D403/12;C07D409/14;C07D413/14;C07D417/14 |
主分类号 |
C07D209/42 |
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