发明名称 MULTIPLE-EPITOPE FUSION PROTEIN
摘要 <P>PROBLEM TO BE SOLVED: To provide a more highly-sensitive method for diagnosing HCV. <P>SOLUTION: The method diagnoses HCV with use of a multiple copy epitope sequence having general structural formula (I): (A)x-(B)y-(C)z, wherein (I) is a linear amino acid sequence; B is an amino acid sequence containing at least five and not more than 1,000 amino acids, in which the amino acids correspond to a naturally-occurring antigenic determinant of an organism; A and C are respectively amino acid sequences different from B and are each independently an amino acid sequence containing at least five and not more than 1,000 amino acids, which amino acids represent a naturally-occurring antigenic determinant that is not adjacent to B in nature; y is an integer of 2 or more; and x and z are each independently an integer wherein x+z is 1 or more. <P>COPYRIGHT: (C)2007,JPO&INPIT
申请公布号 JP2007127671(A) 申请公布日期 2007.05.24
申请号 JP20070027374 申请日期 2007.02.06
申请人 CHIRON CORP 发明人 VALENZUELA PABLO D T;CHIEN DAVID YING
分类号 G01N33/53;G01N33/576;C07K14/155;C07K14/18;C12N15/09;C12P21/04;C12Q1/68;G01N33/569 主分类号 G01N33/53
代理机构 代理人
主权项
地址