KIFS AS MODIFIERS OF THE RHO PATHWAY AND METHODS OF USE
摘要
Human KIF23 genes are identified as modulators of the RHO pathway, and thus are therapeutic targets for disorders associated with defective RHO function. Methods for identifying modulators of RHO, comprising screening for agents that modulate the activity of KIF23 are provided.
申请公布号
CA2629473(A1)
申请公布日期
2007.05.24
申请号
CA20062629473
申请日期
2006.11.09
申请人
EXELIXIS, INC.
发明人
HEUER, TIMOTHY S.;LICKTEIG, KIM;NICOLL, MONIQUE;BJERKE, LYNN MARGARET;ADAMKEWICZ, JOANNE;AMUNDSEN, CRAIG D.;FRANCIS, GEORGE ROSS
