PARTIAL MODULATION VIA PULSED FLOW MODULATOR FOR COMPREHENSIVE TWO-DIMENSIONAL LIQUID OR GAS CHROMATOGRAPHY

摘要

A multi-dimensional chromatographic apparatus and method uses partial modulation. A first sample-containing carrier (100) is supplied to a first column (30) via injector (20). A second carrier is supplied from modulator (50) to connector (60) to supply the second column (70) and detector (80). The modulator (50) provides the second carrier at first and second flow rates, and the first carrier (100) is not stopped or its temperature altered.