发明名称 |
TC-83-DERIVED ALPHAVIRUS VECTORS, PARTICLES AND METHODS. |
摘要 |
The present disclosure provides TC-83 VEE-derived replicons, alphaviral replicon particles and immunogenic compositions containing TC-83 alphaviral replicon particles which direct the expression of at least one antigen when introduced into a suitable host cell. The TC-83 VEE-derived ARPs described herein are improved in that they are subject to a lower vector-specific immune response than prior art ARPs. |
申请公布号 |
MXPA06013124(A) |
申请公布日期 |
2007.05.23 |
申请号 |
MX2006PA13124 |
申请日期 |
2005.05.18 |
申请人 |
ALPHAVAX, INC. |
发明人 |
JON O. RAYNER;JONATHAN F. SMITH;BOLYN HUBBY;ELIZABETH A. REAP |
分类号 |
A61K39/12;A61K39/21;A61K48/00;C07K14/16;C07K14/18;C12N5/10;C12N7/04;C12N15/00;C12N15/09;C12N15/63;C12N15/70;C12N15/74;C12N15/86;C12P21/06 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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