USE OF AMPHIREGULIN AS A PROTECTIVE AGENT IN ACUTE HEPATIC INJURY.

摘要

The invention relates to the use of amphiregulin in the production of a medicament whichcan be used to treat acute hepatic injury and which is administered, for example,in order to: promote a primary endogenous protective reaction in the hepatictissue against acute hepatic injury, promote DNA synthesis in hepatocytes, preventthe death of hepatocytes in the hepatic tissue of patients with acute hepaticinjury, stimulate the regeneration of the remaining hepatic parenchyma followingan acute hepatic injury of any aetiology, and stimulate hepatic regeneration followinga partial hepatectomy. According to the invention, the amphiregulin is administeredas a hepatoprotector medicine for patients with acute hepatic injury of any aetiologyand/or as a hepatoprotector medicine and stimulant of hepatocytic regenerationfor recipients of a liver transplant from a living donor or a cadaver donor.