发明名称 DNA immunization against Chlamydia infection
摘要 Nucleic acid, including DNA, for immunization to generate a protective immune response in a host, including humans, to a major outer membrane protein of a strain of Chlamydia, preferably contains a nucleotide sequence encoding a MOMP or a MOMP fragment that generates antibodies that specifically react with MOMP and a promoter sequence operatively coupled to the first nucleotide sequence for expression of the MOMP in the host. The non-replicating vector may be formulated with a pharmaceutically-acceptable carrier for in vivo administration to the host.
申请公布号 US7220423(B2) 申请公布日期 2007.05.22
申请号 US20040964670 申请日期 2004.10.15
申请人 UNIVERSITY OF MANITOBA 发明人 BRUNHAM ROBERT C.
分类号 A61K39/118;C12N15/09;A61K31/711;A61K39/00;A61P33/00;C07H19/00;C07H21/02;C07K1/00;C07K14/295;C07K16/12;C07K16/40;C12N15/31 主分类号 A61K39/118
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