发明名称 |
EXTENDED RELEASE ACETAMINOPHEN |
摘要 |
An extended release acetaminophen composition comprises particles containing acetaminophen coated on sugar/starch seeds. The particles are present as a blend of both an immediate release and a controll ed release form. The composition, when contained within a gelatin capsule and assayed in a USP Apparatus I rotating basket at 50 rpm i n 900 mL of phosphate buffer at pH 5.8 and a temperature of 37 .degree.C, exhibits about 40 percent acetaminophen dissolution at one- half hour, about 55 percent acetaminophen dissolution at one hour, and substantially complete dissolution of acetaminophen at six hours. A process for treating a human patient with the extended release acetaminophen composition is also disclosed.
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申请公布号 |
CA2339942(C) |
申请公布日期 |
2007.05.22 |
申请号 |
CA19992339942 |
申请日期 |
1999.09.03 |
申请人 |
ASCENT PEDIATRICS, INC. |
发明人 |
MENDES, ROBERT W.;ANAEBONAM, ALOYSIUS O.;CLEMENTE, EMMETT |
分类号 |
A61K9/16;A61K9/50;A61K9/54;A61K31/167 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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