DOMAINS OF EXTRACELLULAR REGION OF HUMAN PLATELET DERIVED GROWTH FACTOR RECEPTOR POLYPEPTIDES

摘要

Defined constructs of modified human platelet-derived growth factor receptor polypeptides are provided. Extracellular re-gion domain structures are identified and modifications and combinatorial rearrangements of the receptor segments are pro-vided. Both cell bound and soluble forms of modified segments are made available, as are methods for assays using them, allowing for screening or ligand analogues.