发明名称 NOVEL COMPOUNDS FOR THE TREATMENT AND PREVENTION OF DIABETES
摘要 This invention is directed to a composition effective for the prevention, treatment, and cure of type II diabetes also known as non-insulin-dependent diabetes mellitus. The composition comprises extracts obtained from several medicinal plants proved effective in reducing blood glucose levels in diabetic animals. The possible mechanism of action of the composition involves a combination of increased expression of insulin receptors in hepatocytes and skeletal muscle, increased insulin secretion in pancreatic .beta. cells, an inhibition of .alpha.--glucohydrolase activity, and an increase in the levels of the GLUT (glucose transporter)2 protein in pancreatic B cells. The composition also proved effective in reducing blo od glucose levels and restoring the general health of diabetic humans. A preferred composition for the treatment of type II diabetes is comprised of extracts obtained from Orthosiphon aristatu s, Cornus officinalis, Trichosanthes kirilowii maxim, Ophiopogon japonicus, and Morus folium.</SDOA B>
申请公布号 CA2206012(C) 申请公布日期 2007.05.22
申请号 CA19972206012 申请日期 1997.05.23
申请人 EASTWOOD BIOMEDICAL RESEARCH INC. 发明人 JUN, HEE-SOOK;YOON, JI-WON
分类号 A61K36/8968;A61K36/00;A61K36/40;A61K36/428;A61K36/53;A61K36/605;A61P3/10 主分类号 A61K36/8968
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