摘要 |
<p>The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula (VI), or a salt thereof, wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP> and R' are as defined in the specification, and processes of manufacturing this compound including intermediates.</p> |
申请人 |
NOVARTIS AG;NOVARTIS PHARMA GMBH;MYKYTIUK, JOHN;BONNET, LUDOVIC;GORSUCH, STEPHAN;ICHIHARA, OSAMU;MEARS, RICHARD;RICHARDSON, CHRISTINE |
发明人 |
MYKYTIUK, JOHN;BONNET, LUDOVIC;GORSUCH, STEPHAN;ICHIHARA, OSAMU;MEARS, RICHARD;RICHARDSON, CHRISTINE |