STEROID FORMULATION AND METHODS OF TREATMENT USING SAME

摘要

The invention provides steroid-containing pharmaceutical compositions which are free of classical preservatives and preferably comprise a steroid that is sparingly soluble or substantially insoluble in water, particulate steroid having an average particle size of from about 2.2 to about 10 microns. Pharmaceutical compositions consisting essentially of particulate triamcinolone acetonide, methylcellulose or hydroxy(C₁-C₈)alkylmethylcellulose, an pharmaceutically acceptable salt, and water are provided by the invention, which compositions are substantially free of non-saccharide polymers and preservatives. The pharmaceutical compositions can be used to treat medical conditions, including ophthalmological conditions and pain.