A process for separating a protein from a sample containing a mixture of proteins is disclosed. The process comprises forming an aqueous combination comprising the sample and an ion exchange material at a pH which is less than the pI of a first fraction of the proteins in the aqueous dispersion but greater than the pI of a second fraction of the proteins in the aqueous dispersion. This process requires no expensive, specialized instrumentation, can be quickly performed, and is carried out in non-denaturing conditions, allowing for the separated proteins to be further studied. The process may be used to remove albumin from a biological sample.
申请公布号
WO2006096479(A3)
申请公布日期
2007.05.18
申请号
WO2006US07509
申请日期
2006.03.02
申请人
FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.;SANG, QING-XIANG (AMY);SAHAB, ZIAD, JOSEPH