DEVICE FOR THE DELIVERY OF BIOACTIVE AGENTS AND A METHOD OF MANUFACTURE.

摘要

The present invention consists of an implantable structural element for in vivocontrolled delivery of bioactive active agents to a situs in a body. The implantablestructural element may be configured as an implantable prosthesis, such as anendoluminal stent, cardiac valve, osteal implant or the like, which serves adual function of being prosthetic and a carrier for a bioactive agent. Controlover elution of the bioactive agents occurs through a plurality of cantilever-likecover members which prevent drug elution until an endogenous or exogenous stimuluscauses the cover members to open and permit drug elution.