<p>The present invention provides expression vectors that facilitate high levels of expression of GPCR proteins. Encompassed by the invention are methods and compositions for recombinant cell lines expressing GPCR proteins with the aid of the expression vectors of the instant invention. The recombinant cell lines of the instant invention express GPCR proteins at levels of at least about 150,000 copies of the protein per cell. The present invention also provides methods and compositions for raising antibodies against GPCR proteins using the high expressing recombinant cells of the instant invention.</p>
申请公布号
WO2007055823(A2)
申请公布日期
2007.05.18
申请号
WO2006US38023
申请日期
2006.09.29
申请人
MULTISPAN, INC.;MANCEBO, HELENA, S.;HER, JENG-HORNG;LI, SAMUEL, X.;WANG, JIANFU, J.
发明人
MANCEBO, HELENA, S.;HER, JENG-HORNG;LI, SAMUEL, X.;WANG, JIANFU, J.