发明名称 |
RATIONAL EVOLUTION OF CYTOKINES FOR HIGHER STABILITY, THE CYTOKINES AND ENCODING NUCLEIC ACID MOLECULES |
摘要 |
Processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided is a rational method for generating protein variants and the resulting variants.
|
申请公布号 |
WO2004022593(A8) |
申请公布日期 |
2007.05.18 |
申请号 |
WO2003IB04347 |
申请日期 |
2003.09.08 |
申请人 |
NAUTILUS BIOTECH;GANTIER, RENE;GUYON, THIERRY;VEGA, MANUEL;DRITTANTI, LILA |
发明人 |
GANTIER, RENE;GUYON, THIERRY;VEGA, MANUEL;DRITTANTI, LILA |
分类号 |
A61K38/00;C07K14/475;C07K14/505;C07K14/52;C07K14/53;C07K14/535;C07K14/54;C07K14/555;C07K14/575;C07K14/61;C12N15/19;C12N15/20;C12N15/24 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|