发明名称 4 [(2,4-DICHLORO-5-METHOXYPHENYL)AMINO]-6-ALKOXY-7-ETHYNYL-3- QUINOLINECARBONITRILES FOR THE TREATMENT OF ISCHEMIC INJURY.
摘要 <p>This invention relates to compounds of the formula (I): wherein: R is methyl orethyl; R' and R" are independently alkyl of 1 to 3 carbon atoms, or R'and R", taken together with the nitrogen to which they are attached, canform a 5 or 6 membered saturated ring which may optionally contain an additionalheteroatom selected from NR"', O or S(O)n; n is 0-2; andR"' is hydrogen or alkyl of 1 to 3 carbon atoms; and pharmaceuticallyacceptable salts thereof, and their use for inhibiting vascular permeabilitycaused by disease, injury or other trauma.</p>
申请公布号 MX2007004833(A) 申请公布日期 2007.05.16
申请号 MX20070004833 申请日期 2005.10.21
申请人 WYETH. 发明人 DIANE HARRIS BOSCHELLI;MARGARET ZALESKA;ANA CAROLINA BARRIOS-SOSA
分类号 A61P9/10;C07D215/44 主分类号 A61P9/10
代理机构 代理人
主权项
地址