发明名称 TROPAN COMPOUND
摘要 The conventional anticholinergic drugs for administration through inhalation have been considered to have the possibility of aggravating dysuria associated with prostatic hyperplasia mediated by blood, and it has been demanded that the conventional anticholinergic drugs for administration through inhalation will have to show reduced side effects or adverse ractions. The present invention relates to a compound represented by the general formula (I): (wherein A represents; and R 1 , R 2 , R 3 and R 1 each a hydrogen atom or a substituent; R 5 is a substituent; X - is an anion;the symbol: denotes an exo-form or endo-form, or their mixture), its salt or solvation product thereof. They are useful as a prophylactic and/or therapeutic agent with reduced side effects or adverse reactions for the diseases mediated by the muscarinic receptor.
申请公布号 EP1785421(A1) 申请公布日期 2007.05.16
申请号 EP20050774538 申请日期 2005.08.29
申请人 ONO PHARMACEUTICAL CO., LTD. 发明人 NAKAI, HISAO;NISHIYAMA, TOSHIHIKO;NAKAMURA, NOBUYUKI;FUJITA, MANABU
分类号 C07D451/06;A61K9/72;A61K31/46;A61K45/00;A61P11/00;A61P11/06;A61P11/08;A61P43/00 主分类号 C07D451/06
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