| 发明名称 |
PSCA: Prostate stem cell antigen and uses thereof |
| 摘要 |
The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors. It also provides antibodies to PSCA. Further, methods of detection/diagnosis and treatment, as well as a transgenic animal are provided. |
| 申请公布号 |
EP1780268(A3) |
申请公布日期 |
2007.05.16 |
| 申请号 |
EP20060021129 |
申请日期 |
1999.12.02 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
REITER, ROBERT;WITTE, OWEN |
| 分类号 |
A01K67/02;C12N5/20;A01K67/027;A61K35/76;A61K38/00;A61K39/395;A61K45/00;A61K47/48;A61K48/00;A61P15/00;A61P35/00;C07K14/47;C07K14/705;C07K16/18;C07K16/28;C07K16/30;C07K16/42;C07K16/46;C12N5/10;C12N15/02;C12N15/09;C12N15/12;C12N15/85;C12P21/00;C12P21/08;C12Q1/02;C12Q1/68;G01N33/53;G01N33/566;G01N33/574;G01N33/577;G01N33/58;G01N33/68 |
主分类号 |
A01K67/02 |
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