Menetelmä tromboosiin ja/tai huonoon antikoagulanttivasteeseen aktivoituun proteiini C:hen liittyvän geenivirheen läsnäolon seulomiseksi

摘要

Method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein C (APC). The method is directed at detecting one or more mutations at one or more of the cleavage and/or binding sites for APC of Factor V and/or Factor Va or at Factor VIII and/or Factor VIIIa at either nucleic acid or protein level or both.