Medical device with plasma cross-linked hydrophilic coating

摘要

A medical device with a hydrophilic and lubricious coating, wherein the coating includes a hydrophilic polymeric unit layer deposited on the medical device and cross-linked with a plasma deposited double bond monomer. The hydrophilic polymeric unit can include ethylene oxide with one or more primary or secondary alcohol groups or glycosaminoglycans such as hyaluronic acid, and the double bond monomer includes monomers containing at least one double bond, preferably a C-C, C-N or C-O bond, including N-trimethylsilyl-allylamine, ethylene, propylene and allyl alcohol.