发明名称 Prostaglandin D2 antagonist
摘要 Disclosed herein is compound 1 or a pharmaceutically acceptable salt, or a prodrug thereof. Compound 1 is useful for treating or preventing a variety of diseases or conditions. Results presented herein also demonstrate that Compound 1 is a prostaglandin D<SUB>2 </SUB>antagonist, and as such is useful in the treatment or prevention of prostaglandin D<SUB>2 </SUB>mediated conditions or diseases. A method comprising administering a prostaglandin D<SUB>2 </SUB>antagonist to a mammal suffering from a disease or condition selected from the group consisting of the gastrointestinal tract disorders or diseases, hyperalgesia, allodynia, abdominal cramping, glaucoma, ocular hypertension, and ocular hypotension is also disclosed herein. Pharmaceutical compositions and products comprising compound 1 are also disclosed.
申请公布号 US7217725(B2) 申请公布日期 2007.05.15
申请号 US20040780441 申请日期 2004.02.12
申请人 ALLERGAN, INC. 发明人 KRAUSS ACHIM H.;WOODWARD DAVID;DONDE YARIV;BURK ROBERT M.
分类号 A61K31/421;C07D263/32;C07D493/08 主分类号 A61K31/421
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