发明名称 |
Composite particles, derived conjugates, preparation method and applications |
摘要 |
The invention relates to composite particles comprising a hydrophobic polymer core and inorganic nanoparticles. Said hydrophobic polymer forms a polymer matrix inside which the inorganic nanoparticles are stabilized and distributed in a relatively homogenous manner. Said particles are at least partially surrounded by an amphophilic copolymer comprising a hydrophobic part and a hydrophilic part, said hydrophobic part being at least partially immobilized in the polymer matrix. The inventor also relates to the preparation method thereof, the conjugates comprising such particles and a ligand and the use of same in reactants and therapeutic compositions.
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申请公布号 |
US7217457(B2) |
申请公布日期 |
2007.05.15 |
申请号 |
US20040475709 |
申请日期 |
2004.02.04 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
ELAISSARI ABDELHAMID;MONTAGNE FRANCK;BOSC ERIC;PICHOT CHRISTIAN;MANDRAND BERNARD;BIBETTE JEROME;MONDAIN-MONVAL OLIVIER |
分类号 |
B32B5/16;G01N33/543;A61K9/14;A61K9/50;A61K9/58;A61K31/74;A61K41/00;A61K47/48;A61K49/18;A61P43/00;C08F2/44;C08F291/00;C08F292/00;C08K3/00;C08K9/08;G01N33/545;G01N33/553 |
主分类号 |
B32B5/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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