| 摘要 |
A medicinal composition which comprises an insulin resistance-improving drug and vitamin B<SUB>1 </SUB>or derivative thereof. In this medicinal composition, the side effects of the insulin resistance-improving drug such as edema, heart enlargement, anemia, etc. are prevented by using vitamin B<SUB>1 </SUB>or its derivative together. It is usable as a remedy for diabetes, a remedy for lifestyle related diseases, an anti-tumor agent, an anti-rheumatoid drug and so on.
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