Recombined cell system for deorphanizing g protein-coupled receptors

摘要

The present invention relates to a recombinant cellular system, comprising an animal host cell, comprising a recombinant G protein-coupled specific receptor, and the recombinant Ca2+ specific channel CNGA2. The invention furthermore relates to a method for producing the cellular system according to the invention and the use of the system for a deorphanisation of G protein-coupled receptors. Furthermore, the present invention relates to the use of the cellular system for identifying novel G protein-coupled receptors from gene banks.