| 摘要 |
The invention provides in part methods of treating cancers of a specific organ or tissue by administering an composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The formulations of the invention thereby facilitate activation of an immune response to a cancer in a particular tissue or organ. In some embodiments, microbial species of the endogenous flora which are capable of causing infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions. The administration of the immunogenic compositions may be repeated relatively frequently over a relatively long period of time, in a dosage that reproduces a consistent visible inflammatory reaction at the successive site or sites of administration, which may for example be by intradermal or subcutaneous injection.
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