发明名称 |
Polymeric delivery formulations of leuprolide with improved efficacy |
摘要 |
The present invention is directed to a flowable composition that is suitable for use as a controlled release implant. The flowable composition includes a biodegradable thermoplastic polyester that is at least substantially insoluble in aqueous medium or body fluid. The flowable composition also includes a biocompatible polar aprotic solvent. The biocompatible polar aprotic solvent is miscible to dispersible in aqueous medium or body fluid. The flowable composition also includes leuprolide acetate. |
申请公布号 |
US2007104759(A1) |
申请公布日期 |
2007.05.10 |
申请号 |
US20060643505 |
申请日期 |
2006.12.21 |
申请人 |
QLT USA, INC. |
发明人 |
DUNN RICHARD L.;GARRETT JOHN S.;RAVIVARAPU HARISH;CHANDRASHEKAR BHAGYA L. |
分类号 |
A61K9/06;A61K38/09;A61F2/02;A61K;A61K9/00;A61K9/16;A61K9/42;A61K38/22;A61K47/06;A61K47/14;A61K47/16;A61K47/20;A61K47/22;A61K47/34;A61M37/00;A61P5/04;A61P13/08;A61P15/00;A61P15/08;A61P35/00 |
主分类号 |
A61K9/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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