| 摘要 |
FIELD: chemistry of metalloorganic compounds, medicine, oncology. ^ SUBSTANCE: invention relates to a method for synthesis of physiologically active compounds, namely: cis-cis-[4-nitraminopyridin-N]tetrachloroplatinum (IV) trimethylolaminomethane salt of the formula: PtCl4 . 2Li wherein Li means compound of the formula: . Method involves interaction of 4-nitraminopyridine with potassium hexachloroplatinate followed by separating formed cis-bis-(4-nitramino-N)tetrachloroplatinum, its treatment with trimethylolaminomethane and isolation of the end substance. Synthesized compound can be used in medicinal practice as both a separate low-toxic anti-metastatic medicinal agent and in composition with the known preparations. ^ EFFECT: valuable medicinal properties of compound, improved method of synthesis. ^ 2 cl, 1 ex |
