发明名称 CRYSTALLINE FORMS OF 3-[5-CHLORO-4-[(2,4-DIFLUOROBENZYL) OXY]-6-OXOPYRIMIDIN-1(6H)-YL]-N-(2-HYDROXYETHYL)-4-METHYLBENZAM IDE.
摘要 <p>Crystalline forms of the p38 kinase inhibitor 3-[5-chloro-4- [(2,4 idifluorobenzyl) oxy]-6-oxopyrimidin-1(6H)-yl]-N-(2-hydroxyethyl)-4-methylbenzam ide is provided. Also provided are combinations and pharmaceutical compositions comprising the crystalline forms and methods for the prophylaxis and/or treatment of a p38 kinase-mediated condition comprising administering to a subject a therapeutically effective amount of the crystalline forms.</p>
申请公布号 MX2007004514(A) 申请公布日期 2007.05.09
申请号 MX20070004514 申请日期 2005.10.03
申请人 PHARMACIA & UPJOHN COMPANY LLC. 发明人 JON G. SELBO
分类号 C07D239/52 主分类号 C07D239/52
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