发明名称 |
Directed switch-mediated DNA recombination |
摘要 |
Switch regions derived from an immunoglobulin (Ig) gene are used to direct recombination between (1) a targeting construct containing a promoter and a switch region (S1) and (2) a target locus minimally containing a promoter, a switch region (S2) and a target sequence. |
申请公布号 |
EP1714971(A3) |
申请公布日期 |
2007.05.09 |
申请号 |
EP20060014556 |
申请日期 |
1997.03.19 |
申请人 |
AMGEN FREMONT INC.;JAPAN TOBACCO INC. |
发明人 |
JAKOBOVITS, AYA |
分类号 |
C07H21/04;C12N15/09;C07K14/00;C07K16/00;C12N1/21;C12N5/00;C12N5/08;C12N15/00;C12N15/10;C12N15/79;C12P21/02;C12P21/08;C12R1/91 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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