发明名称 Lipid-conjugated polyamide compounds
摘要 In accordance with the present invention, there are provided lipid-conjugated polyamide compounds and related compositions and methods thereof. Lipid-conjugated polyamide compounds of the present invention are particularly useful as vehicles for delivering biologically active agents to a target site. In particular, the invention compounds are effective at facilitating the delivery of polynucleotides to cells. The present invention also provides a method for producing stable formulations of polynucleotides complexed with a delivery vehicle.
申请公布号 US7214384(B2) 申请公布日期 2007.05.08
申请号 US20030445642 申请日期 2003.05.27
申请人 NOVARTIS VACCINES AND DIAGNOSTICS, INC. 发明人 ZUCKERMANN RONALD N.;HUANG CHIN-YI;MURPHY JOHN E.;UNO TETSUO
分类号 A61K9/127;C12N15/09;A61K31/711;A61K47/16;A61K47/34;A61K47/48;A61K48/00;C07C231/00;C07C231/02;C07C237/22;C08G69/48;C08K5/20;C12N15/00;C12N15/87 主分类号 A61K9/127
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