| 摘要 |
The invention relates to a solid support for use in cell cultivation in vitr o, comprising a 3D-matrix material and hollow fibres being permeable to at least gaseous oxygen and/or gaseous carbon dioxide, a biological reactor for the cultivation and/or maintenance of living cells comprising said solid support, as well as a method for culturing and/o r maintaining living cells, using said solid support and/or said biological reactor. The solid support, biological reactor and method are especially suited for culturing human or animal derived liver cells, for use in or as a bio-artificial liver. The invention further relates to su ch a bio-artificial liver, as well as a method for treating liver disorders using said bio-artificial liver.
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