ENZYME DETECTION AND MEASUREMENT

摘要

A UNITARY SINGLE USE ANALYTIC DEVICE FOR DETECTING AN ENZYME IN A LIQUID. THE DEVICE COMPRISES A SUPPORT STRUCTURE (1) FOR MANUAL MANIPULATION AND A COMPOSITION ASSOCIATED THEREWITH WHICH IS RESPONSIVE TO THE ENZYME IN SUCH A WAY AS TO CAUSE A CHANGE IN APPEARANCE OF THE DEVICE. THE DEVICE MAY BE ADAPTED FOR DETECTING AN ENZYMES FROM A PLURALITY OF CLASSES BY HAVING COMPOSITIONS SELECTIVELY RESPONSIVE TO AN ENZYME OF ONE CLASS, EACH RESPONDING IN SUCH A WAY AS TO CAUSE A CHANGE IN APPEARANCE OF THE DEVICE INDICATIVE OF THE PRESENCE OF AN ENZYME OF A RESPECTIVE CLASS. ALSO DISCLOSED IS A METHOD FOR ESTIMATING THE ACTIVITY OF AN ENZYME IN A LIQUID COMPRISING THE STEPS OF INSERTING A TEST STRIP OF THE PRESENT INVENTION INTO THE LIQUID AND MEASURING THE TIME TAKEN FROM THE MOMENT OF INSERTION UNTIL A PREDETERMINED CHANGE IN APPEARANCE OF THE TEST STRIP IS OBSERVED, OR NOTING THE APPEARANCE OF THE STRIP AFTER PREDETERMINED TIME.(FIGURE 1)