| 摘要 |
The invention relates to intermediates of formulaor a salt thereof, where Ris a fluorine atom, Ris a hydrogen atom or a fluorine atom, Ror Rare hydrogen atoms, Ra is a cyano group or an aminocarbonyl group, Re is a hydrogen atom, -C (=X) –Y-Rc or Rb, where Rb is a protective group, for example, a tertbutoxycarbonyl group, a trityl group, an o-nitrobenzolesulphenyl group etc., Rc is a leaving group, e.g. a halogen atom, a methanesulfonyl group etc, of a hydroxy group. The intermediates are used in the synthesis of novel cyanopyrrolidine derivatives. |
