摘要 |
This invention concerns a new family of phosphorus-containing compounds containing a moiety JQA- in which: A is absent or is -O-, -S- or –NR-;Q is absent or (if A is -O-, -S- or –NR-) Q may be -V-, -OV-, -SV-, or –NRV-, where V is an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety, such that J is linked to the cyclohexyl ring directly, through A or through VA, OVA, SVA or NRVA J = I - or - II, K is O or S each occurrence of Y is independently -O-, -S-, -NR-, or chemical bond linking a Rmoiety to P and the other variables are as defined herein. |
申请人 |
ARIAD GENETHERAPEUTICS, INC. |
发明人 |
BERSTEIN DAVID, L.;METCALF CHESTER, A., III;ROZAMUS LEONARD, W.;WANG YIHAN |