发明名称 DERIVATIVE OF 5-METHOXY-8-ARYL[1,2,4]-TRIAZOLE[1,5-a]PYRIDINE
摘要 FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention describes a novel derivative of 5-methoxy-8-aryl[1,2,4]-triazole[1,5-a]pyridine of the general formula (I): wherein R1 means hydrogen, halogen atom or lower alkoxy-group; R2 means -C(O)-phenyl wherein ring can be unsubstituted or substituted with one or two substitutes chosen from group consisting of halogen atom, lower alkyl, lower alkoxy-group or trifluoromethyl, or it means -C(O)-furanyl or -C(O)-thiophenyl wherein rings are not substituted or substituted with halogen atom, and its pharmaceutically acceptable salts. Proposed compounds can be used in treatment of diseases associated with adenosine A2 receptors. Also, invention describes a medicinal agent used in treatment of diseases associated with adenosine A2A receptors containing compound of the formula (I) and pharmaceutically acceptable excipients. ^ EFFECT: valuable medicinal properties of agent. ^ 8 cl, 1 tbl, 1 ex
申请公布号 RU2298009(C2) 申请公布日期 2007.04.27
申请号 RU20040114277 申请日期 2002.09.28
申请人 F.KHOFFMANN-LJA ROSH AG 发明人 NETTEKOVEN GENRIKH MATTIAS;SHMITT SEBAST'EN
分类号 C07D471/04;A61K31/437;A61P9/10;A61P11/06;A61P11/16;A61P25/00;A61P25/04;A61P25/08;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P37/08;A61P43/00 主分类号 C07D471/04
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