发明名称 |
Target protein of antidiabetic and novel antidiabetic insuful corresponding thereto |
摘要 |
The present invention is intended to elucidate a molecular target of an antidiabetic such as a thiazolidine derivative. The present invention provides a screening method for an antidiabetic, comprising the steps of: bringing a candidate substance to be screened into contact with a protein represented by the following (a) or (b): (a) a protein comprising the amino acid sequence represented by SEQ ID NO: 2; or (b) a protein comprising an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 2 with the deletion, substitution, addition, or insertion of one or plural amino acids and interacting with the antidiabetic; and detecting the interaction between the candidate substance and the protein.
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申请公布号 |
US2007093536(A1) |
申请公布日期 |
2007.04.26 |
申请号 |
US20040569791 |
申请日期 |
2004.11.16 |
申请人 |
SUWA YORIMASA;YAMADA TSUYOSHI;OSAKI HIRONORI;FURUYA MINORU |
发明人 |
SUWA YORIMASA;YAMADA TSUYOSHI;OSAKI HIRONORI;FURUYA MINORU |
分类号 |
A61K31/426;C07D277/34;C07H21/04;C07K14/47;C07K14/705;G01N33/68 |
主分类号 |
A61K31/426 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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