| 发明名称 |
ORALE PHARMAZEUTISCHE ZUSAMMENSETZUNGEN MIT VERZÖGERTER FREISETZUNG ENTHALTEND 5,8,14-TRIAZATETRACYCLO (10.3.1.0(2,11) 0 (4,9) )-HEXADECA-2(11) 3, 5,7, 9-PENTAENE |
| 摘要 |
<p>The present invention is directed to controlled-release (CR) oral pharmaceutical dosage forms of 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene, 1, and pharmaceutically acceptable salts thereof, and methods of using them to reduce nicotine addiction or aiding in the cessation or lessening of tobacco use while reducing nausea as an adverse effect. The present invention also relates to an immediate-release (IR) low dosage composition having a stable formulation with uniform drug distribution and potency.</p> |
| 申请公布号 |
DE60218885(D1) |
申请公布日期 |
2007.04.26 |
| 申请号 |
DE2002618885 |
申请日期 |
2002.11.04 |
| 申请人 |
PFIZER PRODUCTS INC. |
发明人 |
AM ENDE, MARY TANYA;ROY, MICHAEL CHRISTOPHER;SMITH, SAN DIEGO;WATERMAN, GROTON;MOSES, GROTON;QUAN, GROTON |
| 分类号 |
A61K9/22;A61K47/38;A61K9/20;A61K9/26;A61K9/28;A61K31/495;A61K31/4985;A61K47/02;A61K47/10;A61K47/34;A61K47/36;A61P1/00;A61P1/04;A61P3/04;A61P9/00;A61P9/10;A61P9/12;A61P25/02;A61P25/06;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P25/34;A61P25/36;A61P37/02 |
主分类号 |
A61K9/22 |
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