发明名称 METHOD OF ACTING UPON ORGANISM BY TARGETED DELIVERY OF BIOLOGICALY ACTIVE SUBSTANCES INTO M ITOCHONDRIA, PHARMACEUTICAL COMPOSITION FOR CARRYING OUT SAID METHOD, AND COMPOUND USED FOR THE PURPOSE
摘要 <p>This invention relates to biology and medicine and, in particular, can be used in medicine to make a pharmaceutical composition for targeted delivery of biologically active substances into mitochondria, driven by proton electro-chemical potential in the mitochondria. This invention also relates to the method to affect an organism by the targeted delivery of biologically active compounds to mitochondria. The invention can be useful in treatment of diseases or disorders associated with not normal functioning of mitochondria, in particular diseases associated with increased production of free radicals and reactive oxygen species.</p>
申请公布号 WO2007046729(A1) 申请公布日期 2007.04.26
申请号 WO2006RU00394 申请日期 2006.07.24
申请人 LIMITED LIABILITY COMPANY "MITOTECHNOLOGY";SKULACHEV, VLADIMIR PETROVICH 发明人 SKULACHEV, VLADIMIR PETROVICH
分类号 A61K31/665;A61K31/122;A61K38/04;A61P35/00;A61P39/06;A61P43/00;C07F9/54;C07K4/00 主分类号 A61K31/665
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