METHODS FOR ALTERING SURFACE CHARACTERISTICS OF MICROSPHERES
摘要
Various methods for forming dyed microspheres are provided. One method includes activating a chemical structure coupled to a dye using heat or light to form a reaction intermediate in the presence of a microsphere. The reaction intermediate covalently attaches to a polymer of the microsphere thereby coupling the dye to the polymer and forming the dyed microsphere. Additional methods are provided for forming a dyed microsphere coupled to a molecule. These methods include dyeing the microspheres as described above in addition to synthesizing the molecule on an outer surface of the dyed microspheres. A population of dyed microspheres is also provided. Each of the dyed microspheres of the population includes a dye attached to a polymer of each of the dyed microspheres by a chemical structure. A coefficient of variation in dye characteristics of the population of dyed microspheres attributable to the dye is less than about 10%.
申请公布号
WO2006044275(A3)
申请公布日期
2007.04.26
申请号
WO2005US36264
申请日期
2005.10.11
申请人
LUMINEX CORPORATION;LUGADE, ANANDA, G.;HOFFACKER, KURT, D.