SYNTHESIS OF 2-METHYL-4-(4-METHYL-1-PIPERAZINYL)-10H-THIENO[2, 3-B][1,5]BENZODIAZEPINE AND SALTS THEREOF
摘要
The invention belongs to the field of organic chemistry and relates to a new process for the purification of olanzapine comprising preparation of acid addition salts of olanzapine and transformation thereof into a pharmaceutically acceptable pure and discoloured final product. The present invention also relates to new processes for the preparation of pure olanzapine.
申请公布号
WO2005090359(A3)
申请公布日期
2007.04.26
申请号
WO2005EP02876
申请日期
2005.03.17
申请人
LEK PHARMACEUTICALS D.D.;MESAR, TOMAZ;COPAR, ANTON;STURM, HUBERT;LUDESCHER, JOHANNES
发明人
MESAR, TOMAZ;COPAR, ANTON;STURM, HUBERT;LUDESCHER, JOHANNES